Tomato extracts can fight stomach cancer: Study

Dhaka,  Wed,  23 August 2017
Published : 15 May 2017, 20:52:36
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Tomato extracts can fight stomach cancer: Study

Tomato extracts can inhibit the growth and malignant cloning of stomach cancer cells, according to a new study that paves the way for novel therapies to treat the deadly disease.

Researchers analysed whole tomato extracts for their ability to tackle gastric cancer cell lines.

“Their anti-tumoral effect seem not related to specific components, such as lycopene, but rather suggest that tomatoes should be considered in their entirety,” said Daniela Barone, researcher at the Oncology Research Centre of Mercogliano (CROM) in Italy.

Extracts of San Marzano and Corbarino tomato varieties were able to inhibit the growth and cloning behaviour of malignant cells.

Treatment with the whole tomato extracts affected key processes within the cells hindering their migration ability, arresting cell cycle through the modulation of retinoblastoma family proteins and specific cell cycle inhibitors, and ultimately inducing cancer cell death through apoptosis.

Tomatoes are consumed worldwide and are a staple of the Mediterranean diet, which is popularly thought to lower cancer risk.

Various tomato components have also been analysed for their ability to counteract tumour growth in experimental systems, although few studies have analysed the effects of tomatoes in their entirety.

The research was published in the Journal of Cellular Physiology, according to PTI.

 
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